(a) Acceptable daily intake (ADI). The ADI for total residue of albendazole is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerances for albendazole 2-aminosulfone (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 0.2 ppm.

(ii) Muscle: 0.05 ppm.

(2) Sheep. (i) Liver (target tissue): 0.25 ppm.

(ii) Muscle: 0.05 ppm.

(3) Goat. (i) Liver (target tissue): 0.25 ppm.

(ii) [Reserved]

(c) Related conditions of use. See §§ 520.38a and 520.38b of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of altrenogest is 0.04 µg/kg of body weight per day.

(b) Tolerances. The tolerances for altrenogest (marker residue) are:

(1) Swine. (i) Liver (target tissue): 4 ppb.

(ii) Muscle: 1 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 520.48 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for amoxicillin is:

(1) Cattle. Edible tissues: 0.01 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.88d, 520.88e, 522.88, and 526.88 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerances for ampicillin are:

(1) Cattle. Edible tissues: 0.01 ppm.

(2) Swine. Edible tissues: 0.01 ppm.

(c) Related conditions of use. See §§ 520.90c, 522.90a, and 522.90b of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18120, Apr. 1, 2020]

(a) [Reserved]

(b) Tolerances. The tolerances for amprolium are:

(1) Cattle. (i) Liver, kidney, and muscle: 0.5 ppm.

(ii) Fat: 2.0 ppm.

(2) Chickens and turkeys. (i) Liver and kidney: 1 ppm.

(ii) Muscle: 0.5 ppm.

(iii) Eggs:

(A) Egg yolks: 8 ppm.

(B) Whole eggs: 4 ppm.

(3) Pheasants. (i) Liver: 1 ppm.

(ii) Muscle: 0.5 ppm.

(c) Related conditions of use. See §§ 520.100, 558.55, and 558.58 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of apramycin is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerance for apramycin (marker residue) is:

(1) Swine. Kidney (target tissue): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.110 and 558.59 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of avilamycin is 1.1 mg/kg of body weight per day.

(b) Tolerances. The tolerances for avilamycin are:

(1) Chickens. Edible tissues (excluding eggs): Not required.

(2) Swine. Edible tissues: Not required.

(c) Related conditions of use. See § 558.68 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of azaperone is 0.63 µg/kg of body weight per day.

(b) Tolerances. The tolerance for azaperone is:

(1) Swine. Edible tissues: Not required.

(2) [Reserved]

(c) Related conditions of use. See § 522.150 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of bacitracin is 0.05 mg/kg of body weight per day.

(b) Tolerances. The tolerances for bacitracin are:

(1) Cattle. Edible tissues: 0.5 ppm.

(2) Chickens, turkeys, pheasants, quail. Edible tissues: 0.5 ppm.

(3) Swine. Edible tissues: 0.5 ppm.

(c) Related conditions of use. See §§ 520.154a, 520.154c, 558.76, and 558.78 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for bambermycins are:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.

(3) Swine. Edible tissues: Not required.

(c) Related conditions of use. See § 558.95 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of zilpaterol is 0.083 µg/kg of body weight per day.

(b) Tolerances. The tolerance for zilpaterol freebase (marker residue) is:

(1) Cattle. (i) Liver (target tissue): 12 ppb.

(ii) Muscle: 10 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 558.665 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) [Reserved]

(b) Tolerances. The tolerances for zoalene and its metabolite 3-amino-5-nitro-o-toluamide are:

(1) Chickens. (i) Liver and kidney: 6 ppm.

(ii) Muscle: 3 ppm.

(iii) Fat: 2 ppm.

(2) Turkeys. Liver and muscle: 3 ppm.

(c) Related conditions of use. See § 558.680 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for quinoxaline-2-carboxylic acid (marker residue) is:

(1) Swine. Liver (target tissue): 30 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 558.115 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for carbomycin is:

(1) Chickens. Edible tissues (excluding eggs): Zero.

(2) [Reserved]

(c) Related conditions of use. See § 520.1664 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 88 FR 55567, Aug. 16, 2023]

(a) Acceptable daily intake and acute reference dose—(1) Acceptable daily intake (ADI). The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.

(2) Acute reference dose (ARfD). The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.

(b) Tolerances. The tolerances for desfuroylceftiofur (marker residue) are:

(1) Cattle. (i) Kidney (target tissue): 0.4 ppm.

(ii) Liver: 2 ppm.

(iii) Muscle: 1 ppm.

(iv) Milk: 0.1 ppm.

(2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.

(3) Goats. (i) Kidney (target tissue): 8 ppm.

(ii) Liver: 2 ppm.

(iii) Muscle: 1 ppm.

(iv) Milk: 0.1 ppm.

(4) Sheep. Edible tissues (excluding milk): Not required.

(5) Swine. (i) Kidney (target tissue): 0.25 ppm.

(ii) Liver: 3 ppm.

(iii) Muscle: 2 ppm.

(c) Related conditions of use. See §§ 522.313a, 522.313b, 522.313c, and 526.313 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for cephapirin are:

(1) Cattle. (i) Edible tissues (excluding milk): 0.1 ppm.

(ii) Milk: 0.02 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 526.363 and 526.365 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of chloramine-T is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerance for para-toluenesulfonamide (marker residue) is:

(1) Fish. Muscle/skin (target tissue): 0.9 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 529.382 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for chlorhexidine is:

(1) Cattle. Edible tissues (excluding milk): Zero.

(2) [Reserved]

(c) Related conditions of use. See § 529.400 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of tetracyclines including chlortetracycline, oxytetracycline, and tetracycline is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for the sum of tetracycline residues are:

(1) Cattle. (i) Liver: 6 ppm.

(ii) Kidney and fat: 12 ppm.

(iii) Muscle: 2 ppm.

(2) Chickens, turkeys, and ducks. (i) Liver: 6 ppm.

(ii) Kidney and fat: 12 ppm.

(iii) Muscle: 2 ppm.

(iv) Eggs: 0.4 ppm for chlortetracycline only.

(3) Sheep. (i) Liver: 6 ppm.

(ii) Kidney and fat: 12 ppm.

(iii) Muscle: 2 ppm.

(4) Swine. (i) Liver: 6 ppm.

(ii) Kidney and fat: 12 ppm.

(iii) Muscle: 2 ppm.

(c) Related conditions of use. See §§ 520.441, 520.443, 520.445, 558.128, and 558.140 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for clopidol are:

(1) Chickens and turkeys. (i) Liver and kidney: 15 ppm.

(ii) Muscle: 5 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.175 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of clorsulon is 8 µg/kg of body weight per day.

(b) Tolerances. The tolerances for clorsulon (marker residue) are:

(1) Cattle. (i) Kidney (target tissue): 1.0 ppm.

(ii) Muscle: 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.462 and 522.1193 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for cloxacillin is:

(1) Cattle. Edible tissues: 0.01 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 526.464 and 526.465 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 86 FR 13188, Mar. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerance for colistimethate is:

(1) Chickens. Edible tissues (excluding eggs): Not required.

(2) [Reserved]

(c) Related conditions of use. See § 522.468 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for coumaphos (measured as coumaphos and its oxygen analog, O,O-diethyl O-3- chloro-4-methyl-2-oxo-2 H-1- benzopyran-7-yl phosphate) are:

(1) Chickens. (i) Edible tissues (excluding eggs): 1 ppm.

(ii) Eggs: 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.185 of this chapter.

[86 FR 14821, Mar. 19, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of danofloxacin is 2.4 µg/kg of body weight per day.

(b) Tolerances. The tolerances for danofloxacin (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 0.2 ppm.

(ii) Muscle: 0.2 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 522.522 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of decoquinate is 75 µg/kg of body weight per day.

(b) Tolerances. The tolerances for decoquinate are:

(1) Cattle. (i) Muscle: 1 ppm.

(ii) Other edible tissues (excluding milk): 2 ppm.

(2) Chickens. (i) Muscle: 1 ppm.

(ii) Other edible tissues (excluding eggs): 2 ppm.

(3) Goats. (i) Muscle: 1 ppm.

(ii) Other edible tissues (excluding milk): 2 ppm.

(c) Related conditions of use. See §§ 520.534 and 558.195 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerance for dichlorvos is:

(1) Swine. Edible tissues: 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.596 and 558.198 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of diclazuril is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for diclazuril are:

(1) Chickens and turkeys. (i) Liver: 3 ppm.

(ii) Muscle: 0.5 ppm.

(iii) Skin/fat: 1 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.205 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerances for dihydrostreptomycin are:

(1) Cattle. (i) Kidney: 2.0 ppm.

(ii) Other edible tissues (excluding milk): 0.5 ppm.

(iii) Milk: 0.125 ppm.

(2) Swine. (i) Kidney: 2.0 ppm.

(ii) Other edible tissues: 0.5 ppm.

(c) Related conditions of use. See §§ 522.650, 526.1696b, and 526.1696c of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of doramectin is 0.75 µg/kg of body weight per day.

(b) Tolerances. The tolerances for doramectin (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 300 ppb.

(ii) Muscle: 30 ppb.

(2) Swine. Liver (target tissue): 160 ppb.

(c) Related conditions of use. See §§ 522.770, 522.772, and 524.770 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 88 FR 16549, Mar. 20, 2023]

(a) Acceptable daily intake (ADI). The ADI for total residue of efrotomycin is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerance for efrotomycin is:

(1) Swine. Edible tissues: Not required.

(2) [Reserved]

(c) Related conditions of use. See § 558.235 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of enrofloxacin is 3 µg/kg of body weight per day.

(b) Tolerances. The tolerances for enrofloxacin are:

(1) Cattle. Liver (target tissue): 0.1 ppm desethylene ciprofloxacin (marker residue).

(2) Swine. Liver (target tissue): 0.5 ppm enrofloxacin (marker residue).

(c) Related conditions of use. See §§ 516.812 and 522.812 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of eprinomectin is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerances for eprinomectin B1a (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 1.5 ppm.

(ii) Muscle: 100 ppb.

(iii) Milk: 12 ppb.

(2) [Reserved]

(c) Related conditions of use. See §§ 522.814 and 524.814 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for erythromycin are:

(1) Cattle. (i) Edible tissues (excluding milk): 0.1 ppm.

(ii) Milk: Zero.

(2) Chickens and turkeys. (i) Edible tissues (excluding eggs): 0.125 ppm.

(ii) Eggs: 0.025 ppm.

(c) Related conditions of use. See §§ 520.823, 522.820, 526.820, and 558.248 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) [Reserved]

(b) Residues. Residues of estradiol are not permitted in excess of the following increments above the concentrations of estradiol naturally present in untreated animals:

(1) Cattle. (i) Muscle: 0.2 ppb.

(ii) Liver: 0.6 ppb.

(iii) Kidney: 1.2 ppb.

(iv) Fat: 1.2 ppb.

(2) [Reserved]

(c) Related conditions of use. See §§ 522.840, 522.850, 522.1940, 522.2343, 522.2477, and 522.2478 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 87 FR 17947, Mar. 29, 2022]

(a) [Reserved]

(b) Tolerances. The tolerances for ethopabate, measured as metaphenetidine, are:

(1) Chickens. (i) Liver: 1.5 ppm.

(ii) Kidney: 1.5 ppm.

(iii) Muscle: 0.5 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.58 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for famphur including its oxygen analog is:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.1242g, 524.900, and 558.254 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of fenbendazole is 40 µg/kg of body weight per day.

(b) Tolerances. The tolerances for fenbendazole are:

(1) Cattle. (i) Liver (target tissue): 0.8 ppm fenbendazole (marker residue).

(ii) Milk: 0.22 ppm fenbendazole sulfoxide (marker residue).

(2) Chickens. (i) Liver (target tissue): 5.2 ppm fenbendazole sulfone (marker residue).

(ii) Eggs: 1.8 ppm fenbendazole sulfone (marker residue).

(3) Goats. (i) Liver (target tissue): 0.8 ppm fenbendazole (marker residue).

(ii) [Reserved]

(4) Swine. (i) Liver (target tissue): 3.2 ppm fenbendazole (marker residue).

(ii) [Reserved]

(5) Turkeys. (i) Liver (target tissue): 6 ppm fenbendazole sulfone (marker residue).

(ii) [Reserved]

(c) Related conditions of use. See §§ 520.905a, 520.905b, 520.905c, 520.905d, and 558.258 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 57998, Oct. 20, 2021; 86 FR 61686, Nov. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of fenprostalene is 0.08 µg/kg of body weight per day.

(b) Tolerances. The tolerances for fenprostalene are:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) Swine. Edible tissues: Not required.

(c) Related conditions of use. See § 522.914 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for fenthion is:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 524.920 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of florfenicol is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerances for florfenicol amine (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 3.7 ppm.

(ii) Muscle: 0.3 ppm.

(2) Swine. (i) Liver (target tissue): 2.5 ppm.

(ii) Muscle: 0.2 ppm.

(3) Catfish. Muscle (target tissue): 1 ppm.

(4) Freshwater-reared warmwater finfish (other than catfish) and salmonids. Muscle/skin (target tissue): 1 ppm.

(c) Related conditions of use. See §§ 520.955, 522.955, 522.956, and 558.261 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of flunixin is 0.72 µg/kg of body weight per day.

(b) Tolerances. The tolerances for flunixin are:

(1) Cattle. (i) Liver (target tissue): 125 ppb flunixin free acid (marker residue).

(ii) Muscle: 25 ppb flunixin free acid.

(iii) Milk: 2 ppb 5-hydroxy flunixin (marker residue).

(2) Swine. (i) Liver (target tissue): 30 ppb flunixin free acid (marker residue).

(ii) Muscle: 25 ppb flunixin free acid.

(c) Related conditions of use. See §§ 522.956, 522.970, 522.1664, and 524.970 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of gamithromycin is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerances for gamithromycin (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 500 ppb.

(ii) Muscle: 150 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 522.1014 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of gentamicin is 60 µg/kg of body weight per day.

(b) Tolerances. The tolerances for gentamicin are:

(1) Chickens and turkeys. Edible tissues (excluding eggs): 0.1 ppm.

(2) Swine. (i) Liver: 0.3 ppm.

(ii) Kidney (target tissue): 0.4 ppm gentamicin (marker residue).

(iii) Fat: 0.4 ppm.

(iv) Muscle: 0.1 ppm.

(c) Related conditions of use. See §§ 520.1044a, 520.1044b, 520.1044c, 522.1044, 524.1044e, and 529.1044b of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 13188, Mar. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for residues of total gonadotropins (human chorionic gonadotropin and pregnant mare serum gonadotropin) is 42.25 International Units per kilogram of body weight per day.

(b) Tolerances. The tolerances for gonadotropin are:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) Fish. Edible tissues: Not required.

(3) Swine. Edible tissues: Not required.

(c) Related conditions of use. See §§ 522.1079 and 522.1081 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) Acceptable daily intake (ADI). The ADI for total residue of halofuginone hydrobromide is 0.7 µg/kg of body weight per day.

(b) Tolerances. The tolerances for halofuginone (marker residue) are:

(1) Chickens. Liver (target tissue): 0.16 ppm.

(2) Turkeys. Liver (target tissue): 0.13 ppm.

(c) Related conditions of use. See § 558.265 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for haloxon is:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.1120a and 520.1120b of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for ampicillin (marker residue for hetacillin) are:

(1) Cattle. Edible tissues: 0.01 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 526.1130 of this chapter.

[84 FR 53311, Oct. 7, 2019]

(a) [Reserved]

(b) Tolerances. The tolerances for hygromycin B are:

(1) Chickens. Edible tissues: Zero.

(2) Swine. Edible tissues: Zero.

(c) Related conditions of use. See § 558.274 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of ivermectin is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerances for 22,23-dihydroavermectin B1a (marker residue) are:

(1) American bison. Liver (target tissue): 15 ppb.

(2) Cattle. (i) Liver (target tissue): 1.6 ppm.

(ii) Muscle: 650 ppb.

(3) Reindeer. Liver (target tissue): 15 ppb.

(4) Sheep. Liver (target tissue): 30 ppb.

(5) Swine. (i) Liver (target tissue): 20 ppb.

(ii) Muscle: 20 ppb.

(c) Related conditions of use. See §§ 520.1192, 520.1195, 520.1197, 522.1192, 522.1193, 524.1193, and 558.300 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) Acceptable daily intake (ADI). The ADI for total residue of ketoprofen is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerances for ketoprofen (marker residue) are:

(1) Cattle. (i) Kidney (target tissue): 0.36 ppm.

(ii) [Reserved]

(c) Related conditions of use. See §§ 522.1225 and 522.2632 of this chapter.

[86 FR 61686, Nov. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of laidlomycin is 7.5 µg/kg of body weight per day.

(b) Tolerances. The tolerance for laidlomycin (marker residue) is:

(1) Cattle. Liver (target tissue): 0.2 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.305 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of lasalocid is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerances for lasalocid (marker residue) are:

(1) Cattle. Liver (target tissue): 0.7 ppm.

(2) Chickens. (i) Skin with adhering fat (target tissue): 1.2 ppm.

(ii) Liver: 0.4 ppm.

(3) Rabbits. Liver (target tissue): 0.7 ppm.

(4) Sheep. Liver (target tissue): 1.0 ppm.

(5) Turkeys. (i) Liver (target tissue): 0.4 ppm.

(ii) Skin with adhering fat: 0.4 ppm.

(c) Related conditions of use. See § 558.311 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for levamisole are:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) Sheep. Edible tissues (excluding milk): 0.1 ppm.

(3) Swine. Edible tissues: 0.1 ppm.

(c) Related conditions of use. See §§ 520.1242a, 520.1242b, 520.1242d, 520.1242e, 520.1242f, 520.1242g, 522.1242, and 524.1240 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of lincomycin is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for lincomycin are:

(1) Chickens. Edible tissues (excluding eggs): Not required.

(2) Swine. (i) Liver: 0.6 ppm.

(ii) Muscle: 0.1 ppm.

(3) Honey. 750 ppb.

(c) Related conditions of use. See §§ 520.1263b, 522.1260, and 558.325 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020] Editorial Note:At 86 FR 13188, Mar. 8, 2021, in § 556.360, paragraph (c) was amended; however, the amendment could not be incorporated due to inaccurate amendatory instruction.

(a) Acceptable daily intake (ADI). The ADI for total residues of lubabegron is 3 micrograms per kilogram of body weight per day.

(b) Tolerances. The tolerances for lubabegron (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 10 ppb.

(ii) Muscle: 3 ppb.

(iii) Kidney: 20 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 558.330 of this chapter.

[84 FR 12494, Apr. 2, 2019, as amended at 87 FR 17947, Mar. 29, 2022]

(a) [Reserved]

(b) Tolerances. The tolerance for maduramicin (marker residue) is:

(1) Chickens. Fat (target tissue): 0.38 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.340 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for melengestrol is:

(1) Cattle. Fat: 25 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 558.342 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for metoserpate is:

(1) Chickens. Edible tissues (excluding eggs): 0.02 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 520.1422 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of monensin is 12.5 µg/kg of body weight per day.

(b) Tolerances. The tolerances for monensin are:

(1) Cattle. (i) Liver: 0.10 ppm.

(ii) Muscle, kidney, and fat: 0.05 ppm.

(iii) Milk: Not required.

(2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.

(3) Goats. Edible tissues (excluding milk): 0.05 ppm.

(4) Quail. Edible tissues (excluding eggs): Not required.

(c) Related conditions of use. See § 558.355 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of morantel tartrate is 10 µg/kg of body weight per day.

(b) Tolerances. The tolerances for N-methyl-1,3-propanediamine (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 0.7 ppm.

(ii) Milk: Not required.

(2) Goats. (i) Liver (target tissue): 0.7 ppm.

(ii) Milk: Not required.

(c) Related conditions of use. See §§ 520.1450a, 520.1450b, 520.1450c, and 558.360 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of moxidectin is 4 µg/kg of body weight per day.

(b) Tolerances. The tolerances for moxidectin (marker residue) are:

(1) Cattle. (i) Fat (target tissue): 900 ppb.

(ii) Liver: 200 ppb.

(iii) Muscle: 50 ppb.

(iv) Milk: 40 ppb.

(2) Sheep. (i) Fat (target tissue): 900 ppb.

(ii) Liver: 200 ppb.

(iii) Muscle: 50 ppb.

(c) Related conditions of use. See §§ 520.1454, 522.1450, and 524.1450 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of narasin is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerance for narasin (marker residue) is:

(1) Chickens. Abdominal fat (target tissue): 480 ppb.

(2) [Reserved]

(c) Related conditions of use. See §§ 558.363 and 558.364 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of neomycin is 6 µg/kg of body weight per day.

(b) Tolerances. The tolerances for neomycin are:

(1) Cattle. (i) Kidney (target tissue): 7.2 ppm.

(ii) Liver: 3.6 ppm.

(iii) Muscle: 1.2 ppm.

(iv) Fat: 7.2 ppm.

(v) Milk: 0.15 ppm.

(2) Sheep and goats. (i) Kidney (target tissue): 7.2 ppm.

(ii) Liver: 3.6 ppm.

(iii) Muscle: 1.2 ppm.

(iv) Fat: 7.2 ppm.

(v) Milk: 0.15 ppm.

(3) Swine. (i) Kidney (target tissue): 7.2 ppm.

(ii) Liver: 3.6 ppm.

(iii) Muscle: 1.2 ppm.

(iv) Fat: 7.2 ppm.

(4) Turkeys. (i) Skin with adhering fat: 7.2 ppm.

(ii) Liver: 3.6 ppm.

(iii) Muscle: 1.2 ppm.

(c) Related conditions of use. See §§ 520.1484, 524.1600b, 558.365, and 558.455 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residues of nicarbazin (4,4′-dinitrocarbanilide and 2-hydroxy-4,6-dimethylpyrimidine) is 200 µg/kg of body weight per day.

(b) Tolerances. The tolerance for 4,4′-dinitrocarbanilide (marker residue) is:

(1) Chickens. Liver (target tissue): 52 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 558.364 and 558.366 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for novobiocin are:

(1) Cattle. (i) Edible tissues (excluding milk): 1 ppm.

(ii) Milk: 0.1 ppm.

(2) Chickens, turkeys, and ducks. Edible tissues (excluding eggs): 1 ppm.

(c) Related conditions of use. See §§ 526.1590, 526.1696d, and 558.415 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for nystatin are:

(1) Cattle. Edible tissues (excluding milk): Zero.

(2) Chickens and turkeys. Edible tissues: Zero.

(c) Related conditions of use. See §§ 524.1600b and 558.430 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for ormetoprim are:

(1) Chickens, turkeys, ducks, and chukar partridges. Edible tissues (excluding eggs): 0.1 ppm.

(2) Salmonids and catfish. Edible tissues: 0.1 ppm.

(c) Related conditions of use. See § 558.575 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of oxfendazole is 7 µg/kg of body weight per day.

(b) Tolerances. The tolerance for fenbendazole (marker residue) is:

(1) Cattle. Liver (target tissue): 0.8 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.1629 and 520.1630 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total tetracycline residues (chlortetracycline, oxytetracycline, and tetracycline) is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for the sum of tetracycline residues are:

(1) Cattle. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(iv) Milk: 0.3 ppm.

(2) Chickens and turkeys. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(3) Finfish. Muscle (with adhering skin when edible): 2 ppm.

(4) Lobster. Muscle: 2 ppm.

(5) Swine and sheep. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(6) Honey. 750 ppb.

(c) Related conditions of use. See §§ 520.1660c, 520.1660d, 520.1664, 522.1660a, 522.1660b, 522.1662, 522.1664, 529.1660, 558.450, and 558.455 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 88 FR 16549, Mar. 20, 2023, 88 FR 55567, Aug. 16, 2023]

(a) [Reserved]

(b) Tolerances. The tolerances for penicillin are:

(1) Cattle. (i) Edible tissues (excluding milk): 0.05 ppm.

(ii) Milk: Zero.

(2) Chickens. Edible tissues: Zero.

(3) Pheasants and quail. Edible tissues: Zero.

(4) Sheep and swine. Edible tissues: Zero.

(5) Turkeys. Edible tissues (excluding eggs): 0.01 ppm.

(c) Related conditions of use. See §§ 520.1696a, 522.1696a, 522.1696b, 526.1696, 526.1697, and 526.1698 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 86 FR 13188, Mar. 8, 2021]

(a) Acceptable daily intake (ADI). The ADI for total residue of pirlimycin is 0.01 mg/kg of body weight per day.

(b) Tolerances. The tolerances for pirlimycin (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 0.5 ppm.

(ii) Muscle: 0.3 ppm.

(iii) Milk: 0.4 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 526.1810 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for poloxalene is:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.1840 and 558.464 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 14821, Mar. 19, 2021]

(a) [Reserved]

(b) Residues. Residues of progesterone are not permitted in excess of the following increments above the concentrations of progesterone naturally present in untreated animals:

(1) Cattle and sheep. (i) Muscle: 5 ppb.

(ii) Liver: 15 ppb.

(iii) Kidney: 30 ppb.

(iv) Fat: 30 ppb.

(2) [Reserved]

(c) Related conditions of use. See §§ 522.1940 and 529.1940 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for pyrantel are:

(1) Swine. (i) Liver and kidney: 10 ppm.

(ii) Muscle: 1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.2045 and 558.485 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of ractopamine hydrochloride is 1.25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for ractopamine (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 0.09 ppm.

(ii) Muscle: 0.03 ppm.

(2) Swine. (i) Liver (target tissue): 0.15 ppm.

(ii) Muscle: 0.05 ppm.

(3) Turkeys. (i) Liver (target tissue): 0.45 ppm.

(ii) Muscle: 0.1 ppm.

(c) Related conditions of use. See § 558.500 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for robenidine are:

(1) Chickens. (i) Skin and fat: 0.2 ppm.

(ii) Other edible tissues (excluding eggs): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See § 558.515 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of salinomycin is 5 µg/kg of body weight per day.

(b) Tolerances. The tolerances for salinomycin are:

(1) Chickens. Edible tissues (excluding eggs): Not required.

(2) Quail. Edible tissues (excluding eggs): Not required.

(c) Related conditions of use. See § 558.550 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of semduramicin is 3 µg/kg of body weight per day.

(b) Tolerances. The tolerances for semduramicin are:

(1) Chickens. (i) Liver: 400 ppb.

(ii) Muscle: 130 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 558.555 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of spectinomycin is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for spectinomycin are:

(1) Cattle. (i) Kidney (target tissue): 4 ppm spectinomycin (marker residue).

(ii) Muscle: 0.25 ppm.

(2) Chickens and turkeys. Edible tissues (excluding eggs): 0.1 ppm.

(3) Swine. Edible tissues: Not required.

(c) Related conditions of use. See §§ 520.1265, 520.2123b, 520.2123c, 522.2120, and 522.2121 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for streptomycin are:

(1) Cattle and swine. (i) Kidney: 2.0 ppm.

(ii) Other edible tissues (excluding milk): 0.5 ppm.

(2) Chickens. (i) Kidney: 2.0 ppm.

(ii) Other edible tissues (excluding eggs): 0.5 ppm.

(c) Related conditions of use. See § 520.2158 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for sulfachloropyrazine is:

(1) Chickens. Edible tissues (excluding eggs): Zero.

(2) [Reserved]

(c) Related conditions of use. See § 520.2184 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for sulfachlorpyridazine are:

(1) Cattle and swine. Edible tissues (excluding milk): 0.1 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.2200 and 522.2200 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for sulfadimethoxine are:

(1) Catfish and salmonids. Edible tissues: 0.1 ppm.

(2) Cattle. (i) Edible tissues (excluding milk): 0.1 ppm.

(ii) Milk: 0.01 ppm.

(3) Chickens, turkeys, ducks, and chukar partridges. Edible tissues (excluding eggs): 0.1 ppm.

(c) Related conditions of use. See §§ 520.2220a, 520.2220d, 520.2220e, 522.2220, and 558.575 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for sulfaethoxypyridazine are:

(1) Cattle. (i) Edible tissues (excluding milk): 0.1 ppm.

(ii) Milk: Zero.

(2) Swine. Edible tissues: Zero.

(c) Related conditions of use. See §§ 520.2240a, 520.2240b, and 522.2240 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerance for sulfamerazine is:

(1) Trout. Edible tissues: Zero.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.2218 and 558.582 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) [Reserved]

(b) Tolerances. The tolerances for sulfamethazine are:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) Chickens and turkeys. Edible tissues (excluding eggs): 0.1 ppm.

(3) Swine. Edible tissues: 0.1 ppm.

(c) Related conditions of use. See §§ 520.445, 520.2218, 520.2260a, 520.2260b, 520.2260c, 520.2261a, 520.2261b, 522.2260, 558.140, and 558.630 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 86 FR 13188, Mar. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerances for sulfaquinoxaline are:

(1) Cattle. Edible tissues (excluding milk): 0.1 ppm.

(2) Chickens and turkeys. Edible tissues (excluding eggs): 0.1 ppm.

(c) Related conditions of use. See §§ 520.2218, 520.2325a, 520.2325b, and 558.586 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) [Reserved]

(b) Tolerances. The tolerances for sulfomyxin are:

(1) Chickens and turkeys. Edible tissues (excluding eggs): Zero.

(2) [Reserved]

(c) Related conditions of use. See § 522.2340 of this chapter.

(a) [Reserved]

(b) Residues. Residues of testosterone are not permitted in excess of the following increments above the concentrations of testosterone naturally present in untreated animals:

(1) Cattle. (i) Fat: 2.6 ppb.

(ii) Kidney: 1.9 ppb.

(iii) Liver: 1.3 ppb.

(iv) Muscle: 0.64 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 522.2343 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 87 FR 10970, Feb. 28, 2022]

(a) Acceptable daily intake (ADI). The ADI for total tetracycline residues (chlortetracycline, oxytetracycline, and tetracycline) is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for the sum of tetracycline residues are:

(1) Cattle and sheep. (i) Kidney and fat: 12 ppm.

(ii) Liver: 6 ppm.

(iii) Muscle: 2 ppm.

(2) Chickens and turkeys. (i) Kidney and fat: 12 ppm.

(ii) Liver: 6 ppm.

(iii) Muscle: 2 ppm.

(3) Swine. (i) Kidney and fat: 12 ppm.

(ii) Liver: 6 ppm.

(iii) Muscle: 2 ppm.

(c) Related conditions of use. See §§ 520.2345c and 520.2345d of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of tiamulin is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerance for 8-alpha-hydroxymutilin (marker residue) is:

(1) Swine. Liver (target tissue): 0.6 ppm.

(2) [Reserved]

(c) Related conditions of use. See §§ 520.2455 and 558.612 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of tildipirosin is 50 µg/kg of body weight per day.

(b) Tolerances. The tolerance for tildipirosin (the marker residue) is:

(1) Cattle. (i) Liver (the target tissue): 10 ppm.

(ii) [Reserved]

(2) [Reserved]

(c) Related conditions of use. See § 522.2460 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) Acceptable daily intake (ADI). The ADI for total residue of tilmicosin is 25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for tilmicosin (marker residue) are:

(1) Cattle. (i) Liver (target tissue): 1.2 ppm.

(ii) Muscle: 0.1 ppm.

(2) Sheep. (i) Liver (target tissue): 1.2 ppm.

(ii) Muscle: 0.1 ppm.

(3) Swine. (i) Liver (target tissue): 7.5 ppm.

(ii) Muscle: 0.1 ppm.

(c) Related conditions of use. See §§ 520.2471, 522.2471, and 558.618 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of trenbolone is 0.4 µg/kg of body weight per day.

(b) Tolerances. The tolerance for trenbolone is:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) [Reserved]

(c) Related conditions of use. See §§ 522.2476, 522.2477, and 522.2478 of this chapter.

(a) [Reserved]

(b) Tolerances. The tolerances for tripelennamine are:

(1) Cattle. (i) Edible tissues (excluding milk): 200 ppb.

(ii) Milk: 20 ppb.

(2) [Reserved]

(c) Related conditions of use. See § 522.2615 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of tulathromycin is 15 µg/kg of body weight per day.

(b) Tolerances. The tolerances for CP-60,300 (marker residue) are:

(1) Cattle. Liver (target tissue): 5.5 ppm.

(2) Swine. Kidney (target tissue): 15 ppm.

(c) Related conditions of use. See §§ 522.2630 and 522.2632 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 86 FR 61686, Nov. 8, 2021]

(a) [Reserved]

(b) Tolerances. The tolerances for tylosin are:

(1) Cattle. (i) Liver, kidney, fat, and muscle: 0.2 ppm.

(ii) Milk: 0.05 ppm.

(2) Chickens and turkeys. (i) Liver, kidney, fat, and muscle: 0.2 ppm.

(ii) Eggs: 0.2 ppm.

(3) Swine. Liver, kidney, fat, and muscle: 0.2 ppm.

(4) Honey. 500 ppb.

(c) Related conditions of use. See §§ 520.2640, 522.2640, 558.625, and 558.630 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) Acceptable daily intake (ADI). The ADI for total residues of tylvalosin is 47.7 µg/kg of body weight per day.

(b) Tolerances. A tolerance for tylvalosin in edible tissues of swine is not required.

(c) Related conditions of use. See §§ 520.2645 and 558.633 of this chapter.

(a) Acceptable daily intake (ADI). The ADI for total residue of virginiamycin is 250 µg/kg of body weight per day.

(b) Tolerances. The tolerances for virginiamycin are:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) Chickens. Edible tissues (excluding eggs): Not required.

(3) Swine. (i) Kidney, skin, and fat: 0.4 ppm.

(ii) Liver: 0.3 ppm.

(iii) Muscle: 0.1 ppm.

(c) Related conditions of use. See § 558.635 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

(a) Acceptable daily intake (ADI). The ADI for total residue of zeranol is 1.25 µg/kg of body weight per day.

(b) Tolerances. The tolerances for zeranol are:

(1) Cattle. Edible tissues (excluding milk): Not required.

(2) Sheep. Edible tissues (excluding milk): 20 ppb.

(c) Related conditions of use. See § 522.2680 of this chapter.