Appendix B - Appendix B to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities

[CAS Number Order]

CAS No. Chemical name Notes Reportable quantity *
(pounds)
Threshold planning quantity
(pounds)
0Organorhodium Complex (PMN-82-147)1010/10,000 50-00-0Formaldehydef100500 50-07-7Mitomycin C10500/10,000 50-14-6Ergocalciferolb1,0001,000/10,000 51-21-8Fluorouracil500500/10,000 51-75-2Mechlorethamineb1010 51-83-2Carbachol Chloride500500/10,000 54-11-5Nicotineb100100 54-62-6Aminopterin500500/10,000 55-91-4Isofluorphateb100100 56-25-7Cantharidin100100/10,000 56-38-2Parathionb10100 56-72-4Coumaphos10100/10,000 57-14-7Dimethylhydrazine101,000 57-24-9Strychnineb10100/10,000 57-47-6Physostigmine100100/10,000 57-57-8Propiolactone, Beta-10500 57-64-7Physostigmine, Salicylate (1:1)100100/10,000 57-74-9Chlordane11,000 58-36-6Phenoxarsine, 10,10′-Oxydi-500500/10,000 58-89-9Lindane11,000/10,000 59-88-1Phenylhydrazine Hydrochloride1,0001,000/10,000 60-34-4Methyl Hydrazine10500 60-41-3Strychnine sulfate10100/10,000 60-51-5Dimethoate10500/10,000 62-38-4Phenylmercury Acetate100500/10,000 62-53-3Anilinef5,0001,000 62-73-7Dichlorvos101,000 62-74-8Sodium Fluoroacetate1010/10,000 62-75-9Nitrosodimethylamined101,000 64-00-6Phenol, 3-(1-Methylethyl)-, Methylcarbamate10500/10,000 64-86-8Colchicined1010/10,000 65-30-5Nicotine sulfate100100/10,000 66-81-9Cycloheximide100100/10,000 67-66-3Chloroformf1010,000 70-69-9Propiophenone, 4-Amino-c100100/10,000 71-63-6Digitoxinb100100/10,000 72-20-8Endrin1500/10,000 74-83-9Methyl Bromidef1,0001,000 74-90-8Hydrocyanic Acid10100 74-93-1Methyl Mercaptanf100500 75-15-0Carbon Disulfidef10010,000 75-21-8Ethylene Oxidef101,000 75-44-5Phosgenef1010 75-55-8Propyleneimine110,000 75-56-9Propylene Oxidef10010,000 75-74-1Tetramethylleadb, f100100 75-77-4Trimethylchlorosilane1,0001,000 75-78-5Dimethyldichlorosilaned500500 75-79-6Methyltrichlorosilaned500500 75-86-5Acetone Cyanohydrin101,000 76-02-8Trichloroacetyl Chloride500500 77-47-4Hexachlorocyclopentadiened10100 77-78-1Dimethyl Sulfate100500 77-81-6Tabunb, d1010 78-00-2Tetraethylleadb10100 78-34-2Dioxathion500500 78-53-5Amiton500500 78-71-7Oxetane, 3,3-Bis(Chloromethyl)-500500 78-82-0Isobutyronitriled1,0001,000 78-94-4Methyl Vinyl Ketone1010 78-97-7Lactonitrile1,0001,000 79-06-1Acrylamidef5,0001,000/10,000 79-11-8Chloroacetic Acid100100/10,000 79-19-6Thiosemicarbazide100100/10,000 79-21-0Peracetic Acid500500 79-22-1Methyl Chloroformated1,000500 80-63-7Methyl 2-Chloroacrylate500500 81-81-2Warfarin100500/10,000 82-66-6Diphacinone1010/10,000 86-50-0Azinphos-Methyl110/10,000 86-88-4ANTU100500/10,000 88-05-1Aniline, 2,4,6-Trimethyl-500500 88-85-7Dinoseb1,000100/10,000 91-08-7Toluene 2,6-Diisocyanate100100 95-48-7Cresol, o-1001,000/10,000 98-05-5Benzenearsonic Acid1010/10,000 98-07-7Benzotrichloride10100 98-13-5Trichlorophenylsilaned500500 98-16-8Benzenamine, 3-(Trifluoromethyl)-500500 98-87-3Benzal Chloride5,000500 98-95-3Nitrobenzenef1,00010,000 99-98-9Dimethyl-p-Phenylenediamine1010/10,000 100-14-1Benzene, 1-(Chloromethyl)-4-Nitro-500500/10,000 100-44-7Benzyl Chloride100500 102-36-3Isocyanic Acid, 3,4-Dichlorophenyl Ester500500/10,000 103-85-5Phenylthiourea100100/10,000 106-89-8Epichlorohydrinf1001,000 106-96-7Propargyl Bromide1010 107-02-8Acrolein1500 107-07-3Chloroethanol500500 107-11-9Allylamine500500 107-12-0Propionitrile10500 107-13-1Acrylonitrilef10010,000 107-15-3Ethylenediamine5,00010,000 107-16-4Formaldehyde Cyanohydrind1,0001,000 107-18-6Allyl Alcohol1001,000 107-30-2Chloromethyl Methyl Etherb10100 107-44-8Sarind1010 107-49-3TEPP10100 108-05-4Vinyl Acetate Monomerf5,0001,000 108-23-6Isopropyl Chloroformate1,0001,000 108-91-8Cyclohexylaminef10,00010,000 108-95-2Phenol1,000500/10,000 108-98-5Thiophenol100500 109-61-5Propyl Chloroformate500500 109-77-3Malononitrile1,000500/10,000 110-00-9Furan100500 110-57-6Trans-1,4-Dichlorobutene500500 110-89-4Piperidine1,0001,000 111-44-4Dichloroethyl Ether1010,000 111-69-3Adiponitrilef1,0001,000 115-21-9Trichloroethylsilaned500500 115-26-4Dimefox500500 115-29-7Endosulfan110/10,000 115-90-2Fensulfothiond500500 116-06-3Aldicarbb1100/10,000 119-38-0Isopropylmethyl-pyrazolyl Dimethylcarbamate100500 123-31-9Hydroquinonef100500/10,000 123-73-9Crotonaldehyde, (E)-1001,000 124-65-2Sodium Cacodylate100100/10,000 124-87-8Picrotoxin500500/10,000 126-98-7Methacrylonitriled1,000500 129-00-0Pyreneb5,0001,000/10,000 129-06-6Warfarin Sodiumd100100/10,000 140-29-4Benzyl Cyanided500500 140-76-1Pyridine, 2-Methyl-5-Vinyl-500500 141-66-2Dicrotophos100100 143-33-9Sodium Cyanide (Na(CN))a10100 144-49-0Fluoroacetic Acid1010/10,000 149-74-6Dichloromethylphenylsilane1,0001,000 151-38-2Methoxyethylmercuric Acetate500500/10,000 151-50-8Potassium Cyanidea10100 151-56-4Ethyleneimine1500 152-16-9Diphosphoramide, Octamethyl-100100 297-78-9Isobenzan100100/10,000 297-97-2Thionazin100500 298-00-0Parathion-Methylb100100/10,000 298-02-2Phorate1010 298-04-4Disulfoton1500 300-62-9Amphetamine1,0001,000 302-01-2Hydrazine11,000 309-00-2Aldrin1500/10,000 315-18-4Mexacarbate1,000500/10,000 316-42-7Emetine, Dihydrochlorided11/10,000 327-98-0Trichloronatee500500 353-42-4Boron Trifluoride Compound With Methyl Ether (1:1)1,0001,000 359-06-8Fluoroacetyl Chlorideb1010 371-62-0Ethylene Fluorohydrinb, d1010 379-79-3Ergotamine Tartrate500500/10,000 465-73-6Isodrin1100/10,000 470-90-6Chlorfenvinfos500500 502-39-6Methylmercuric Dicyanamide500500/10,000 504-24-5Pyridine, 4-Amino-d1,000500/10,000 505-60-2Mustard Gasd500500 506-61-6Potassium Silver Cyanidea1500 506-68-3Cyanogen Bromide1,000500/10,000 506-78-5Cyanogen Iodide1,0001,000/10,000 509-14-8Tetranitromethane10500 514-73-8Dithiazanine Iodide500500/10,000 534-07-6Bis(Chloromethyl) Ketone1010/10,000 534-52-1Dinitrocresol1010/10,000 535-89-7Crimidine100100/10,000 538-07-8Ethylbis(2-Chloroethyl)Amined500500 541-25-3Lewisiteb, d1010 541-53-7Dithiobiuret100100/10,000 542-76-7Propionitrile, 3-Chloro-1,0001,000 542-88-1Chloromethyl Etherd10100 542-90-5Ethylthiocyanate10,00010,000 555-77-1Tris(2-Chloroethyl)Amined100100 556-61-6Methyl Isothiocyanatea500500 556-64-9Methyl Thiocyanate10,00010,000 558-25-8Methanesulfonyl Fluoride1,0001,000 563-12-2Ethion101,000 563-41-7Semicarbazide Hydrochloride1,0001,000/10,000 584-84-9Toluene 2,4-Diisocyanate100500 594-42-3Perchloromethylmercaptan100500 597-64-8Tetraethyltinb100100 614-78-8Thiourea, (2-Methylphenyl)-500500/10,000 624-83-9Methyl Isocyanate10500 627-11-2Chloroethyl Chloroformate1,0001,000 630-60-4Ouabainb100100/10,000 639-58-7Triphenyltin Chloride500500/10,000 640-19-7Fluoroacetamide100100/10,000 644-64-4Dimetilan1500/10,000 675-14-9Cyanuric Fluoride100100 676-97-1Methyl Phosphonic Dichloridea100100 696-28-6Phenyl Dichloroarsined1500 760-93-0Methacrylic Anhydride500500 786-19-6Carbophenothion500500 814-49-3Diethyl Chlorophosphated500500 814-68-6Acrylyl Chlorided100100 824-11-3Trimethylolpropane Phosphited100100/10,000 900-95-8Stannane, Acetoxytriphenyl-c500500/10,000 919-86-8Demeton-S-Methyl500500 920-46-7Methacryloyl Chloride100100 944-22-9Fonofos500500 947-02-4Phosfolan100100/10,000 950-10-7Mephosfolan500500 950-37-8Methidathion500500/10,000 991-42-4Norbormide100100/10,000 998-30-1Triethoxysilane500500 999-81-5Chlormequat Chlorided100100/10,000 1031-47-6Triamiphos500500/10,000 1066-45-1Trimethyltin Chloride500500/10,000 1122-60-7Nitrocyclohexane500500 1124-33-0Pyridine, 4-Nitro-,1-Oxide500500/10,000 1129-41-5Metolcarb1,000100/10,000 1303-28-2Arsenic Pentoxide1100/10,000 1306-19-0Cadmium Oxide100100/10,000 1314-62-1Vanadium Pentoxide1,000100/10,000 1314-84-7Zinc Phosphidea100500 1327-53-3Arsenous Oxided1100/10,000 1397-94-0Antimycin Ab1,0001,000/10,000 1420-07-1Dinoterb500500/10,000 1464-53-5Diepoxybutane10500 1558-25-4Trichloro(Chloromethyl)Silane100100 1563-66-2Carbofuran1010/10,000 1600-27-7Mercuric Acetate500500/10,000 1622-32-8Ethanesulfonyl Chloride, 2-Chloro-500500 1752-30-3Acetone Thiosemicarbazide1,0001,000/10,000 1910-42-5Paraquat Dichloride1010/10,000 1982-47-4Chloroxuron500500/10,000 2001-95-8Valinomycinb1,0001,000/10,000 2032-65-7Methiocarb10500/10,000 2074-50-2Paraquat Methosulfate1010/10,000 2097-19-0Phenylsilatraned100100/10,000 2104-64-5EPN100100/10,000 2223-93-0Cadmium Stearateb1,0001,000/10,000 2231-57-4Thiocarbazide1,0001,000/10,000 2238-07-5Diglycidyl Ether1,0001,000 2275-18-5Prothoate100100/10,000 2497-07-6Oxydisulfotond500500 2524-03-0Dimethyl Phosphorochloridothioate500500 2540-82-1Formothion100100 2570-26-5Pentadecylamine100100/10,000 2587-90-8Phosphorothioic Acid, O,O-Dimethyl-S-(2-Methylthio) Ethyl Esterb, c500500 2631-37-0Promecarbd1,000500/10,000 2636-26-2Cyanophos1,0001,000 2642-71-9Azinphos-Ethyl100100/10,000 2665-30-7Phosphonothioic Acid, Methyl-, O-(4-Nitrophenyl) O-Phenyl Ester500500 2703-13-1Phosphonothioic Acid, Methyl-, O-Ethyl O-(4-(Methylthio)Phenyl) Ester500500 2757-18-8Thallous Malonateb, d100100/10,000 2763-96-4Muscimol1,000500/10,000 2778-04-3Endothion500500/10,000 3037-72-7Silane, (4-Aminobutyl)Diethoxymethyl-1,0001,000 3254-63-5Phosphoric Acid, Dimethyl 4-(Methylthio)Phenyl Ester500500 3569-57-1Sulfoxide, 3-Chloropropyl Octyl500500 3615-21-2Benzimidazole, 4,5-Dichloro-2-(Trifluoromethyl)-c500500/10,000 3689-24-5Sulfotep100500 3691-35-8Chlorophacinone100100/10,000 3734-97-2Amiton Oxalate100100/10,000 3735-23-7Methyl Phenkapton500500 3878-19-1Fuberidazole100100/10,000 4044-65-9Bitoscanate500500/10,000 4098-71-9Isophorone Diisocyanateg500500 4104-14-7Phosacetim100100/10,000 4170-30-3Crotonaldehyde1001,000 4301-50-2Fluenetil100100/10,000 4418-66-0Phenol, 2,2′-Thiobis(4-Chloro-6-Methyl)-100100/10,000 4835-11-4Hexamethylenediamine, N,N′-Dibutyl-500500 5344-82-1Thiourea, (2-Chlorophenyl)-100100/10,000 5836-29-3Coumatetralyl500500/10,000 6533-73-9Thallous Carbonateb, d100100/10,000 6923-22-4Monocrotophos1010/10,000 7446-09-5Sulfur Dioxidef500500 7446-11-9Sulfur Trioxidea100100 7446-18-6Thallous Sulfate100100/10,000 7487-94-7Mercuric Chloride500500/10,000 7550-45-0Titanium Tetrachloride1,000100 7580-67-8Lithium Hydridea100100 7631-89-2Sodium Arsenate11,000/10,000 7637-07-2Boron Trifluoride500500 7647-01-0Hydrogen Chloride (gas only)f5,000500 7664-39-3Hydrogen Fluoride100100 7664-41-7Ammoniaf100500 7664-93-9Sulfuric Acid1,0001,000 7697-37-2Nitric Acid1,0001,000 7719-12-2Phosphorus Trichloride1,0001,000 7722-84-1Hydrogen Peroxide (Conc >52%)f1,0001,000 7723-14-0Phosphorusa, d1100 7726-95-6Brominef500500 7778-44-1Calcium Arsenate1500/10,000 7782-41-4Fluorinee10500 7782-50-5Chlorine10100 7783-00-8Selenious Acid101,000/10,000 7783-06-4Hydrogen Sulfidef100500 7783-07-5Hydrogen Selenide1010 7783-60-0Sulfur Tetrafluoride100100 7783-70-2Antimony Pentafluoride500500 7783-80-4Tellurium Hexafluoridee100100 7784-34-1Arsenous Trichloride1500 7784-42-1Arsine100100 7784-46-5Sodium Arsenite1500/10,000 7786-34-7Mevinphos10500 7791-12-0Thallous Chlorideb, d100100/10,000 7791-23-3Selenium Oxychloride500500 7803-51-2Phosphine100500 8001-35-2Camphechlor1500/10,000 8065-48-3Demeton500500 10025-73-7Chromic Chloride11/10,000 10025-87-3Phosphorus Oxychloride1,000500 10026-13-8Phosphorus Pentachloridea500500 10028-15-6Ozone100100 10031-59-1Thallium Sulfated100100/10,000 10102-18-8Sodium Selenited100100/10,000 10102-20-2Sodium Tellurite500500/10,000 10102-43-9Nitric Oxideb10100 10102-44-0Nitrogen Dioxide10100 10124-50-2Potassium Arsenite1500/10,000 10140-87-1Ethanol, 1,2-Dichloro-, Acetate1,0001,000 10210-68-1Cobalt Carbonyld1010/10,000 10265-92-6Methamidophos100100/10,000 10294-34-5Boron Trichloride500500 10311-84-9Dialifor100100/10,000 10476-95-6Methacrolein Diacetate1,0001,000 12002-03-8Paris Green1500/10,000 12108-13-3Manganese, Tricarbonyl Methylcyclopentadienyld100100 13071-79-9Terbufoshd100100 13171-21-6Phosphamidon100100 13194-48-4Ethoprophos1,0001,000 13410-01-0Sodium Selenate100100/10,000 13450-90-3Gallium Trichloride500500/10,000 13463-39-3Nickel Carbonyl101 13463-40-6Iron, Pentacarbonyl-100100 14167-18-1Salcomine500500/10,000 15271-41-7Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Chloro-6-((((Methylamino)Carbonyl)Oxy)Imino)-, (1s-(1-alpha,2-beta,4-alpha,5-alpha,6E))-500500/10,000 16752-77-5Methomyld100500/10,000 17702-41-9Decaborane(14)500500/10,000 17702-57-7Formparanate100100/10,000 19287-45-7Diborane100100 19624-22-7Pentaborane500500 20830-75-5Digoxind1010/10,000 20859-73-8Aluminum Phosphidea100500 21548-32-3Fosthietan500500 21609-90-5Leptophos500500/10,000 21908-53-2Mercuric Oxide500500/10,000 21923-23-9Chlorthiophosd500500 22224-92-6Fenamiphos1010/10,000 23135-22-0Oxamyl100100/10,000 23422-53-9Formetanate Hydrochlorided100500/10,000 23505-41-1Pirimifos-Ethyl1,0001,000 24017-47-8Triazofos500500 24934-91-6Chlormephos500500 26419-73-8Carbamic Acid, Methyl-, O-(((2,4-Dimethyl-1, 3-Dithiolan-2-yl)Methylene)Amino)-100100/10,000 26628-22-8Sodium Azide (Na(N3))a1,000500 27137-85-5Trichloro(Dichlorophenyl)Silane500500 28347-13-9Xylylene Dichloride100100/10,000 28772-56-7Bromadiolone100100/10,000 30674-80-7Methacryloyloxyethyl Isocyanateh100100 39196-18-4Thiofanox100100/10,000 50782-69-9Phosphonothioic Acid, Methyl-, S-(2-(Bis(1-Methylethyl)Amino)Ethyl) O-Ethyl Ester100100 53558-25-1Pyriminild100100/10,000 58270-08-9Zinc, Dichloro(4,4-Dimethyl-5((((Methylamino) Carbonyl)Oxy)Imino)Pentanenitrile)-, (T-4)-100100/10,000 62207-76-5Cobalt, ((2,2′-(1,2-Ethanediylbis (Nitrilomethylidyne)) Bis(6-Fluorophenolato)) (2-)-N,N′,O,O′)-100100/10,000

* Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.

Notes:

a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non-powder, non-molten, non-solution form.

b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.

c. Chemicals added by final rule, April 22, 1987.

d. Revised TPQ based on new or re-evaluated toxicity data, April 22, 1987.

e. The TPQ was revised due to calculation error, April 22, 1987.

f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”). (November 17, 1986, and February 15, 1990.)

g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987, final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.